NAD+-13C5-1

Modify Date: 2024-04-03 08:38:11

NAD+-13C5-1 Structure
NAD+-13C5-1 structure
Common Name NAD+-13C5-1
CAS Number 1859096-06-2 Molecular Weight 668.39
Density N/A Boiling Point N/A
Molecular Formula C1613C5H27N7O14P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NAD+-13C5-1


NAD+-13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

 Names

Name NAD+-13C5-1

 NAD+-13C5-1 Biological Activity

Description NAD+-13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70.  

[3]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92.  

[4]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12.  

 Chemical & Physical Properties

Molecular Formula C1613C5H27N7O14P2
Molecular Weight 668.39