YIR-819 TFA salt

Modify Date: 2024-04-11 22:42:25

YIR-819 TFA salt Structure
YIR-819 TFA salt structure
Common Name YIR-819 TFA salt
CAS Number 1883372-87-9 Molecular Weight 606.044
Density N/A Boiling Point N/A
Molecular Formula C25H35ClF3N7O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of YIR-819 TFA salt


YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.

 Names

Name YIR-819 TFA salt

 YIR-819 TFA salt Biological Activity

Description YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.
References References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. 2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67. View Related Products by Target HIV

 Chemical & Physical Properties

Molecular Formula C25H35ClF3N7O5
Molecular Weight 606.044
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