YIR-819 TFA salt structure
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Common Name | YIR-819 TFA salt | ||
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CAS Number | 1883372-87-9 | Molecular Weight | 606.044 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C25H35ClF3N7O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of YIR-819 TFA saltYIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
Name | YIR-819 TFA salt |
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Description | YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
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References | References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. 2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67. View Related Products by Target HIV |
Molecular Formula | C25H35ClF3N7O5 |
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Molecular Weight | 606.044 |