Salmefamol

Modify Date: 2024-01-13 17:18:08

Salmefamol Structure
Salmefamol structure
Common Name Salmefamol
CAS Number 18910-65-1 Molecular Weight 331.40600
Density 1.2g/cm3 Boiling Point 553.4ºC at 760mmHg
Molecular Formula C19H25NO4 Melting Point N/A
MSDS N/A Flash Point 288.5ºC

 Use of Salmefamol


Salmeterol is a long-acting beta2-adrenergic receptor agonist drug used in the maintenance and prevention of asthma symptoms and maintenance of chronic obstructive pulmonary disease (COPD) symptoms. Symptoms include shortness of breath, wheezing, coughing and chest tightness. Salmeterol is also used to prevent breathing difficulties during exercise (exercise induced bronchospasm). It is marketed as Serevent in the US.

 Names

Name 4-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]-2-(hydroxymethyl)phenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2g/cm3
Boiling Point 553.4ºC at 760mmHg
Molecular Formula C19H25NO4
Molecular Weight 331.40600
Flash Point 288.5ºC
Exact Mass 331.17800
PSA 81.95000
LogP 2.53820
Vapour Pressure 4.43E-13mmHg at 25°C
Index of Refraction 1.598

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ6438000
CHEMICAL NAME :
1,3-Benzenedimethanol, 4-hydroxy-alpha(sup 1)-(((2-(4-methoxyphenyl)-1-methylethyl)amino) methyl)-
CAS REGISTRY NUMBER :
18910-65-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H25-N-O4
MOLECULAR WEIGHT :
331.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 51,627,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 51,627,1975

 Synonyms

Salmefamolum [INN-Latin]
AHR 3929
AH-3923
a-((p-methoxy-a-methylphenethylamino)methyl)-4-hydroxy-m-xylene-a,a'-diol
Salmefamol
EINECS 242-662-5
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