(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide

Modify Date: 2024-01-09 12:24:56

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure
(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide structure
Common Name (S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
CAS Number 192726-05-9 Molecular Weight 466.61600
Density 1.154g/cm3 Boiling Point 762.223ºC at 760 mmHg
Molecular Formula C27H38N4O3 Melting Point N/A
MSDS N/A Flash Point 414.778ºC

 Names

Name (2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.154g/cm3
Boiling Point 762.223ºC at 760 mmHg
Molecular Formula C27H38N4O3
Molecular Weight 466.61600
Flash Point 414.778ºC
Exact Mass 466.29400
PSA 114.67000
LogP 3.59330
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.577

 Synthetic Route

~%

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure

(S)-N-[(2S,4S,5...

CAS#:192726-05-9

Literature: Abbott Laboratories Patent: EP1170289 A2, 2002 ; Location in patent: Page 65 ;

~%

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure

(S)-N-[(2S,4S,5...

CAS#:192726-05-9

Literature: Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

~%

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure

(S)-N-[(2S,4S,5...

CAS#:192726-05-9

Literature: Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

~%

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure

(S)-N-[(2S,4S,5...

CAS#:192726-05-9

Literature: Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

~%

(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide Structure

(S)-N-[(2S,4S,5...

CAS#:192726-05-9

Literature: Abbott Laboratories Patent: US6372905 B1, 2002 ; Location in patent: Example 3 ;

 Synonyms

(2S,3S,5S)-2-amino-3-hydroxy-5-(2S-(2-oxotetrahydropyrimidin-2-yl)-3-methylbutanoyl)amino-1,6-diphenylhexane
(2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexane-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
(S)-N-[(2S,4S,5S)-5-AMINO-4-HYDROXY-1,6-DIPHENYLHEXAN-2-YL]-3-METHYL-2-(2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)BUTANAMIDE
(|AS)-N-[(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-|A-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
(2S,3S,5S)-2-amino-3-hydroxy-5-(2S-(1-tetrahydro-pyrimid-2-onyl)-3-methylbutanoyl)amino-1,6-diphenylhexane