3-Pyridineacrylic acid

Modify Date: 2024-01-10 16:16:09

3-Pyridineacrylic acid Structure
3-Pyridineacrylic acid structure
Common Name 3-Pyridineacrylic acid
CAS Number 19337-97-4 Molecular Weight 149.15
Density 1.3±0.1 g/cm3 Boiling Point 307.6±17.0 °C at 760 mmHg
Molecular Formula C8H7NO2 Melting Point 232-235ºC
MSDS Chinese USA Flash Point 139.8±20.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 3-Pyridineacrylic acid


trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV)[1].

 Names

Name 3-(3-pyridyl)acrylic acid
Synonym More Synonyms

 3-Pyridineacrylic acid Biological Activity

Description trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV)[1].
Related Catalog
References

[1]. Wu M, et al. Discovery and SARs of trans-3-aryl acrylic acids and their analogs as novel anti-tobacco mosaic virus (TMV) agents. PLoS One. 2013;8(2):e56475.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 307.6±17.0 °C at 760 mmHg
Melting Point 232-235ºC
Molecular Formula C8H7NO2
Molecular Weight 149.15
Flash Point 139.8±20.9 °C
Exact Mass 149.047684
PSA 50.19000
LogP 1.17
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.625
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles1

More Articles
Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011)

Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids ...

 Synonyms

3-Pyridineacrylic acid
trans-3-(3-Pyridyl)acrylic acid
2-Propenoic acid, 3-(3-pyridinyl)-, (2E)-
(2E)-3-(3-Pyridinyl)acrylic acid
(2E)-3-(Pyridin-3-yl)acrylic acid
Pyridine-3-acrylic acid
MFCD00006410
(2E)-3-(pyridin-3-yl)prop-2-enoic acid
3-PYRIDYLACRYLIC ACID
3-PYRIDINYL-ACRYLIC ACID
3-PYRIDIN-3-YL-ACRYLIC ACID
RARECHEM BK HC S246
EINECS 214-424-0
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