GSK8814
Modify Date: 2024-01-12 19:09:41
GSK8814 structure
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Common Name | GSK8814 | ||
|---|---|---|---|---|
| CAS Number | 1997369-78-4 | Molecular Weight | 527.61 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H35F2N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GSK8814GSK8814 is a potent, selective, and ATAD2/2B bromodomain chemical probe and inhibitor, with a binding constant pKd=8.1 and a pKi=8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC50s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1[1]. |
| Name | GSK8814 |
|---|
| Description | GSK8814 is a potent, selective, and ATAD2/2B bromodomain chemical probe and inhibitor, with a binding constant pKd=8.1 and a pKi=8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC50s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1[1]. |
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| Related Catalog | |
| Target |
ATAD2:8.9 (pKi) ATAD2:8 nM (Ki) BRD4 BD1:4.6 (pIC50) |
| References |
| Molecular Formula | C28H35F2N5O3 |
|---|---|
| Molecular Weight | 527.61 |