Propargyl-peg4-sulfone-peg4-t-butyl ester

Modify Date: 2024-01-05 09:53:19

Propargyl-peg4-sulfone-peg4-t-butyl ester structure	Common Name	Propargyl-peg4-sulfone-peg4-t-butyl ester
	CAS Number	2055024-43-4	Molecular Weight	584.72
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₈O₁₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-peg4-sulfone-peg4-t-butyl ester

Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG4-Sulfone-PEG4-Boc
Synonym	More Synonyms

Description	Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₈O₁₂S
Molecular Weight	584.72

MFCD30182061