1-Butanone,1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-,hydrochloride (1:1) structure
|
Common Name | 1-Butanone,1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-,hydrochloride (1:1) | ||
---|---|---|---|---|
CAS Number | 2062-77-3 | Molecular Weight | 445.87800 | |
Density | 1.26g/cm3 | Boiling Point | 515.9ºC at 760mmHg | |
Molecular Formula | C22H24ClF4NO2 | Melting Point | N/A | |
MSDS | USA | Flash Point | 265.8ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Name | Trifluperidol hydrochloride |
---|---|
Synonym | More Synonyms |
Density | 1.26g/cm3 |
---|---|
Boiling Point | 515.9ºC at 760mmHg |
Molecular Formula | C22H24ClF4NO2 |
Molecular Weight | 445.87800 |
Flash Point | 265.8ºC |
Exact Mass | 445.14300 |
PSA | 40.54000 |
LogP | 5.53090 |
Vapour Pressure | 1.8E-11mmHg at 25°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
J. Pharmacol. Exp. Ther. 295 , 226-232, (2000) Clozapine is the prototype atypical antipsychotic drug, producing little or no extrapyramidal side effects, while improving negative symptoms of psychosis. Clozapine's high affinity for serotonin rece... |
|
Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.
J. Pharmacol. Exp. Ther. 296(1) , 150-9, (2001) The use of trifluoroperazine in a well washed rat brain membrane preparation revealed [(3)H]ifenprodil binding to a single high affinity state with the pharmacology of N-methyl-D-aspartate (NMDA) rece... |
|
Flupentixol and trifluperidol reduce interleukin-1 beta and interleukin-2 release by rat mixed glial and microglial cell cultures.
Pol. J. Pharmacol. 56(5) , 563-70, (2004) Neuroleptics penetrate into the brain, where they act not only on neurons but probably also on glial cells. In the available literature, there are no reports on the effect of neuroleptics on cytokine ... |
1-(4-fluorophenyl)-4-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]butan-1-one,hydrochloride |