SR 16832

Modify Date: 2024-01-02 19:39:34

SR 16832 Structure
SR 16832 structure
Common Name SR 16832
CAS Number 2088135-12-8 Molecular Weight 357.748
Density 1.5±0.1 g/cm3 Boiling Point 492.3±45.0 °C at 760 mmHg
Molecular Formula C17H12ClN3O4 Melting Point N/A
MSDS N/A Flash Point 251.5±28.7 °C

 Use of SR 16832


SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.

 Names

Name 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Synonym More Synonyms

 SR 16832 Biological Activity

Description SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.
References References 1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978. View Related Products by Target PPAR

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 492.3±45.0 °C at 760 mmHg
Molecular Formula C17H12ClN3O4
Molecular Weight 357.748
Flash Point 251.5±28.7 °C
Exact Mass 357.051636
LogP 3.70
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.708

 Synonyms

2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro-
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