TETRAPHENYLARSONIUM CHLORIDE HYDROCHLORIDE DIHYDRATE

EMERGENCY OVERVIEW
Toxic by inhalation and if swallowed. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. May cause cardiac disturbances. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. May cause central nervous system depression. Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours.
Inhalation:
The toxicological properties of this substance have not been fully investigated. May be harmful if inhaled. May cause cardiac abnormalities. Inhalation of arsenic compounds may lead to irritation of the respiratory tract and to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation. Inhalation at high concentrations may cause CNS depression and asphixiation.
Chronic:
Chronic exposure to arsenical dust may cause shortness of breath, nausea, chest pains, and garlic odor. Cancer suspect agent.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 21006-74-6: United Kingdom, WEL - TWA: (listed as arsenic compounds, n.o.s.): mg/m3 TWA (except arsine, as As) United Kingdom, WEL - STEL: (listed as arsenic compounds, n.o.s.) 0.3 mg/m3 STEL (except arsine, as As) United States OSHA: 0.5 mg/m3 TWA (listed under Arsenic).
Belgium - TWA: (listed as arsenic): 0.01 mg/m3 VLE Japan: (listed as arsenic compounds, n.o.s.): 3 g/m3 OEL (refere value, as As) Malaysia: (listed as arsenic): 0.01 mg/m3 TWA Netherlands: (listed as arsenic): 0.050 mg/m3 MAC Spain: (listed as arsenic compounds, n.o.s.): 0.1 mg/m3 VLA-ED (a As) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: white - light brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 208 - 213 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: (C6H5)4AsCl.HCl.2H2O
Molecular Weight: 491.28

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, oxides of arsenic.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 21006-74-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Tetraphenylarsonium Chloride Hydrochloride Dihydrate - IARC: Group 1 carcinogen (listed as Arsenic).

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: ORGANOARSENIC COMPOUND, N.O.S.*
Hazard Class: 6.1
UN Number: 3280
Packing Group: II
IMO
Shipping Name: ORGANOARSENIC COMPOUND, N.O.S.
Hazard Class: 6.1
UN Number: 3280
Packing Group: II
RID/ADR
Shipping Name: ORGANOARSENIC COMPOUND, N.O.S.
Hazard Class: 6.1
UN Number: 3280
Packing group: II

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23/25 Toxic by inhalation and if swallowed.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 20/21 When using do not eat, drink or smoke.
S 28A After contact with skin, wash immediately with
plenty of water.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 21006-74-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 21006-74-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 21006-74-6 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A