N,N'-bis-(propargyl-PEG4)-Cy5 (chloride)

Modify Date: 2024-01-02 12:48:12

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) structure	Common Name	N,N'-bis-(propargyl-PEG4)-Cy5 (chloride)
	CAS Number	2107273-08-3	Molecular Weight	819.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₇H₆₃ClN₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N,N'-bis-(propargyl-PEG4)-Cy5 (chloride)

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N,N'-bis-(propargyl-PEG4)-Cy5

Description	N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₇H₆₃ClN₂O₈
Molecular Weight	819.46