3'-O-Ac-dT

Modify Date: 2024-01-02 18:04:39

3'-O-Ac-dT Structure
3'-O-Ac-dT structure
Common Name 3'-O-Ac-dT
CAS Number 21090-30-2 Molecular Weight 284.27
Density 1.42g/cm3 Boiling Point N/A
Molecular Formula C12H16N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-O-Ac-dT


3'-O-Acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-acetylthymidine
Synonym More Synonyms

 3'-O-Ac-dT Biological Activity

Description 3'-O-Acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.42g/cm3
Molecular Formula C12H16N2O6
Molecular Weight 284.27
Exact Mass 284.10100
PSA 110.62000
Index of Refraction 1.576

 Synthetic Route

 Synonyms

MFCD00056059
3'-O-ACETYLTHYMIDINE
Thymidine 3'-acetate
3'-O-acethyl thymidine
3'-O-acetyl-2'-deoxythyMidine
3'-O-Ac-thymidine
3'-acetatethyMidine
3'-O-Ac-dT
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