DACN(Tos2,6-OH)

Modify Date: 2024-07-18 07:38:17

DACN(Tos2,6-OH) structure	Common Name	DACN(Tos2,6-OH)
	CAS Number	2109751-74-6	Molecular Weight	448.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₄N₂O₅S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DACN(Tos2,6-OH)

DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity[1].

Name	DACN(Tos2,6-OH)

Description	DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kazunobu Igawa, et al. Thieme Chemistry Journals Awardees: Where Are They Now? One-Pot Synthesis of Versatile Buckle Units for Click Chemistry: 4,8-Diazacyclononynes (DACNs). Synlett 2017; 28(16): 2110-2114.

Molecular Formula	C₂₁H₂₄N₂O₅S₂
Molecular Weight	448.56

DACN(Tos2,6-OH)

Use of DACN(Tos2,6-OH)

Names

DACN(Tos2,6-OH) Biological Activity

Chemical & Physical Properties