N-Mal-N-bis(PEG4-NHS ester)

Modify Date: 2024-01-10 22:43:19

N-Mal-N-bis(PEG4-NHS ester) Structure
N-Mal-N-bis(PEG4-NHS ester) structure
Common Name N-Mal-N-bis(PEG4-NHS ester)
CAS Number 2112738-60-8 Molecular Weight 858.84
Density N/A Boiling Point N/A
Molecular Formula C37H54N4O19 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Mal-N-bis(PEG4-NHS ester)


N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Mal-N-bis(PEG4-NHS ester)
Synonym More Synonyms

 N-Mal-N-bis(PEG4-NHS ester) Biological Activity

Description N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H54N4O19
Molecular Weight 858.84

 Synonyms

MFCD29912654
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