Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-

Modify Date: 2024-01-14 19:04:38

Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)- structure	Common Name	Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-
	CAS Number	2135-14-0	Molecular Weight	418.49800
	Density	1.27g/cm3	Boiling Point	538.2ºC at 760mmHg
	Molecular Formula	C₂₄H₃₁FO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	279.3ºC

Name	Pregna-1,4-diene-3,20-dione, 9.α.-fluoro-16.α.,17.α.-isopropylidenedioxy-11.β.-hydroxy
Synonym	More Synonyms

Density	1.27g/cm3
Boiling Point	538.2ºC at 760mmHg
Molecular Formula	C₂₄H₃₁FO₅
Molecular Weight	418.49800
Flash Point	279.3ºC
Exact Mass	418.21600
PSA	72.83000
LogP	3.44640
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.573

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU3840000

CHEMICAL NAME :: Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(ox y))-, (11-beta,16-alpha)-

CAS REGISTRY NUMBER :: 2135-14-0

BEILSTEIN REFERENCE NO. :: 0056899

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C24-H31-F-O5

MOLECULAR WEIGHT :: 418.55

WISWESSER LINE NOTATION :: L E5 B666 OV AHTTT&J A1 BF CQ E1 FV1Q FOVR& G1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 194 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,250,1966

Descinolone acetonide

Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16,17-((1-methylethyl idene)bis(oxy))-,(11beta,16alpha)

9-fluoro-11beta-hydroxy-16alpha,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione