(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE

Modify Date: 2024-01-07 18:01:37

(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure
(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE structure
Common Name (4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE
CAS Number 214287-88-4 Molecular Weight 314.69000
Density 1.52g/cm3 Boiling Point 377.9ºC at 760mmHg
Molecular Formula C14H10ClF3N2O Melting Point N/A
MSDS N/A Flash Point 182.4ºC

 Names

Name (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.52g/cm3
Boiling Point 377.9ºC at 760mmHg
Molecular Formula C14H10ClF3N2O
Molecular Weight 314.69000
Flash Point 182.4ºC
Exact Mass 314.04300
PSA 44.62000
LogP 3.42410
Vapour Pressure 6.52E-06mmHg at 25°C
Index of Refraction 1.595

 Synthetic Route

~77%

(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure

(4S)-6-CHLORO-4...

CAS#:214287-88-4

Literature: SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES Patent: EP1614672 A1, 2006 ; Location in patent: Page/Page column 15 ;

~%

(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure

(4S)-6-CHLORO-4...

CAS#:214287-88-4

Literature: Jiang, Biao; Si, Yu-Gui Angewandte Chemie - International Edition, 2004 , vol. 43, # 2 p. 216 - 218

~%

(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure

(4S)-6-CHLORO-4...

CAS#:214287-88-4

Literature: Magnus, Nicholas A.; Confalone, Pat N.; Storace, Louis; Patel, Mona; Wood, Christopher C.; Davis, Wayne P.; Parsons Jr., Rodney L. Journal of Organic Chemistry, 2003 , vol. 68, # 3 p. 754 - 761

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(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure

(4S)-6-CHLORO-4...

CAS#:214287-88-4

Literature: Magnus, Nicholas A.; Confalone, Pat N.; Storace, Louis; Patel, Mona; Wood, Christopher C.; Davis, Wayne P.; Parsons Jr., Rodney L. Journal of Organic Chemistry, 2003 , vol. 68, # 3 p. 754 - 761

~%

(4S)-6-CHLORO-4-(2-CYCLOPROPYLETHYNYL)-4-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE Structure

(4S)-6-CHLORO-4...

CAS#:214287-88-4

Literature: Magnus, Nicholas A.; Confalone, Pat N.; Storace, Louis Tetrahedron Letters, 2000 , vol. 41, # 17 p. 3015 - 3019

 Synonyms

dpc 961