JAK-2/3-IN-2

Modify Date: 2024-01-20 11:16:33

Use of JAK-2/3-IN-2

JAK-2/3-IN-2 (Compound 3h) is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively[1].

Name	JAK-2/3-IN-2

Description	JAK-2/3-IN-2 (Compound 3h) is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK3:18.9 nM (IC50) JAK2:23.85 nM (IC50)
References	[1]. Sanachai K, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega, 2022.

Molecular Formula	C₁₉H₁₉ClN₂OS
Molecular Weight	358.88