PROTAC BRD4 Degrader-2
Modify Date: 2024-01-02 17:37:27
PROTAC BRD4 Degrader-2 structure
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Common Name | PROTAC BRD4 Degrader-2 | ||
|---|---|---|---|---|
| CAS Number | 2185795-53-1 | Molecular Weight | 757.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H39N9O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC BRD4 Degrader-2PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1]. |
| Name | PROTAC BRD4 Degrader-2 |
|---|
| Description | PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon BRD4 BD1:14.2 nM (IC50) |
| In Vitro | PROTAC BRD4 Degrader-2 (Compound 17) inhibits the growth of THP-1 cell line with an IC50 of 1.83±0.016 μM[1]. Cell Proliferation Assay[1] Cell Line: Human monocyte lymphoma cell line THP-1 Concentration: 72 hours Incubation Time: 0.81-3.26 μM Result: Showd high anti-proliferative potency. |
| References |
| Molecular Formula | C40H39N9O7 |
|---|---|
| Molecular Weight | 757.79 |
| Storage condition | 2-8°C |