2,3-Dichloroquinoxaline

Modify Date: 2024-01-01 23:17:41

2,3-Dichloroquinoxaline Structure
2,3-Dichloroquinoxaline structure
Common Name 2,3-Dichloroquinoxaline
CAS Number 2213-63-0 Molecular Weight 199.037
Density 1.5±0.1 g/cm3 Boiling Point 269.7±35.0 °C at 760 mmHg
Molecular Formula C8H4Cl2N2 Melting Point 152-154 °C(lit.)
MSDS Chinese USA Flash Point 142.9±11.5 °C
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name 2,3-Dichloroquinoxaline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 269.7±35.0 °C at 760 mmHg
Melting Point 152-154 °C(lit.)
Molecular Formula C8H4Cl2N2
Molecular Weight 199.037
Flash Point 142.9±11.5 °C
Exact Mass 197.975159
PSA 25.78000
LogP 3.04
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.671
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VD1720000
CHEMICAL NAME :
Quinoxaline, 2,3-dichloro-
CAS REGISTRY NUMBER :
2213-63-0
BEILSTEIN REFERENCE NO. :
0126076
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H4-Cl2-N2
MOLECULAR WEIGHT :
199.04
WISWESSER LINE NOTATION :
T66 BN ENJ CG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
195 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Gastrointestinal - peritonitis Kidney, Ureter, Bladder - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534573
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03256

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;
Risk Phrases R25;R36/37/38
Safety Phrases S26-S36/37/39-S45-S37/39-S28A
RIDADR 2811
WGK Germany 3
RTECS VD1720000
Packaging Group III
Hazard Class 6.1

 Articles5

More Articles
Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents.

Eur. J. Med. Chem. 45 , 1976-81, (2010)

Treatment of 6-aminothiouracil (1) with 2,3-dichloroquinoxaline (2) in ethanol/TEA afforded 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one (3), which was refluxed in DMF to give 2-aminopyr...

Synthesis, structure elucidation and antibacterial evaluation of new steroidal -5-en-7-thiazoloquinoxaline derivatives.

Eur. J. Med. Chem. 43 , 2257-61, (2008)

Some heterocyclic systems namely cholest-5-en-7-thiazolo[4,5-b]quinoxaline-2-yl-hydrazone] were synthesized by the reaction of cholest-5-en-7-one-thiosemicarbazone with 2,3-dichloroquinoxaline at 80 d...

AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents.

Bioorg. Med. Chem. 20(5) , 1711-22, (2012)

A direct and single-step method has been developed for the synthesis of mono and 2,3-disubstituted quinoxalines by using a AlCl(3) induced (hetero)arylation of 2,3-dichloroquinoxaline. Both symmetrica...

 Synonyms

2,3-Dichloroquinoxaline
2,3-DICHLORO-QUINOXALINE
2,3,6-TRIFLUOROBENZOICACID
2,3-dichloroquinoxazoline
2,3-dichloroquinaxoline
Quinoxaline,2,3-dichloro
Quinoxaline, 2,3-dichloro-
EINECS 218-667-3
MFCD00006720
2,3-dichloro quinoxaline
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