4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid

Modify Date: 2024-01-03 17:05:49

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure
4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid structure
Common Name 4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid
CAS Number 2224-10-4 Molecular Weight 300.33100
Density 1.337g/cm3 Boiling Point N/A
Molecular Formula C12H16N2O5S Melting Point 210-212ºC
MSDS USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-Carboxy Tolbutamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.337g/cm3
Melting Point 210-212ºC
Molecular Formula C12H16N2O5S
Molecular Weight 300.33100
Exact Mass 300.07800
PSA 120.95000
LogP 3.03540
Index of Refraction 1.558

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 41
Safety Phrases 26-39
RIDADR NONH for all modes of transport
HS Code 2935009090

 Synthetic Route

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4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 7 p. 2518 - 2519

~%

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 7 p. 2518 - 2519

~%

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 7 p. 2518 - 2519

~%

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Farmaco, Edizione Scientifica, , vol. 12, p. 375,376,378

~%

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Farmaco, Edizione Scientifica, , vol. 12, p. 375,376,378

~%

4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid Structure

4-(N-(Butylcarb...

CAS#:2224-10-4

Literature: Farmaco, Edizione Scientifica, , vol. 12, p. 375,376,378

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles22

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A reliable liquid chromatography/tandem mass spectrometry has been developed for simultaneous evaluation of the activities of five cytochrome P450s (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A) in rat ...

Cytochrome P450 2C9 phenotyping using low-dose tolbutamide.

Eur. J. Clin. Pharmacol. 60(3) , 165-71, (2004)

The hypoglycaemic drug tolbutamide is used for assessment of CYP2C9 activity in vivo. However, therapeutically active doses of 500 mg bear the risk of hypoglycaemia, and a tolbutamide-derived paramete...

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An isocratic, high-performance liquid chromatography method has been developed for simultaneous determination of the oral antidiabetic tolbutamide and two of its metabolites, 4-hydroxytolbutamide and ...

 Synonyms

Carboxytolbutamide
N-Butyl-N'-(4-carboxyphenylsulfonyl)urea
4-(butylcarbamoylsulfamoyl)benzoic acid
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