BRP-201

Modify Date: 2024-01-10 21:30:26

BRP-201 Structure
BRP-201 structure
Common Name BRP-201
CAS Number 2227434-74-2 Molecular Weight 503.06
Density N/A Boiling Point N/A
Molecular Formula C28H27ClN4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BRP-201


Brp-201 is considered as a promising therapeutic target for the next generation of anti-inflammatory drugs in the treatment of inflammatory diseases. It is a new, effective and selective inhibitor of mPGES-1 with an IC50 value of 0.42 μM.

 Names

Name BRP-201

 BRP-201 Biological Activity

Description Brp-201 is considered as a promising therapeutic target for the next generation of anti-inflammatory drugs in the treatment of inflammatory diseases. It is a new, effective and selective inhibitor of mPGES-1 with an IC50 value of 0.42 μM.
Related Catalog
Target

mPGES-1:0.42 μM (IC50)

References

[1]. Ergül AG, et al. Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase. Eur J Med Chem. 2022 Mar 5;231:114167.

 Chemical & Physical Properties

Molecular Formula C28H27ClN4OS
Molecular Weight 503.06