3-Fluoro-4-iodopyridine

Modify Date: 2024-01-02 10:44:48

3-Fluoro-4-iodopyridine Structure
3-Fluoro-4-iodopyridine structure
Common Name 3-Fluoro-4-iodopyridine
CAS Number 22282-75-3 Molecular Weight 222.987
Density 2.0±0.1 g/cm3 Boiling Point 203.1±20.0 °C at 760 mmHg
Molecular Formula C5H3FIN Melting Point 86.8-87.0°C
MSDS Chinese USA Flash Point 76.6±21.8 °C
Symbol GHS05
GHS05
Signal Word Danger

 Use of 3-Fluoro-4-iodopyridine




 Names

Name 3-fluoro-4-iodopyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 203.1±20.0 °C at 760 mmHg
Melting Point 86.8-87.0°C
Molecular Formula C5H3FIN
Molecular Weight 222.987
Flash Point 76.6±21.8 °C
Exact Mass 222.929413
PSA 12.89000
LogP 1.61
Vapour Pressure 0.4±0.4 mmHg at 25°C
Index of Refraction 1.600
Storage condition 2-8°C

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
3-Fluoro-4-iodopyridine
Product Name:
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H314:Causes severe skin burns and eye damage
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P310:Immediately call a POISON CENTER or doctor/physician

Section3. Composition/information on ingredients.
Ingredient name:3-Fluoro-4-iodopyridine
CAS number:22282-75-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
This product should be handled only by, or under the close supervision of, those properly qualified
Handling:
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C5H3FIN
Molecular weight: 223

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride, hydrogen Iodide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN3261Class: 8Packing group: III
Proper shipping name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (3-Fluoro-4-iodopyridine)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xi: Irritant;C: Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3261 8/PG 3
HS Code 2933399090

 Synthetic Route

~63%

3-Fluoro-4-iodopyridine Structure

3-Fluoro-4-iodo...

CAS#:22282-75-3

Literature: Awad, Hacan; Mongin, Florence; Trecourt, Francois; Queguiner, Guy; Marsais, Francis; Blanco, Fernando; Abarca, Belen; Ballesteros, Rafael Tetrahedron Letters, 2004 , vol. 45, # 36 p. 6697 - 6701

 Preparation


 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Fluoro-4-iodopyridine
3-fluoro-4-iodo-pyridine
MFCD03092927
4-Iodo-3-fluoropyridine
Pyridine, 3-fluoro-4-iodo-
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