terbuthylazine d5

Modify Date: 2024-01-14 12:59:06

terbuthylazine d5 Structure
terbuthylazine d5 structure
Common Name terbuthylazine d5
CAS Number 222986-60-9 Molecular Weight 234.741
Density 1.2±0.1 g/cm3 Boiling Point 373.1±25.0 °C at 760 mmHg
Molecular Formula C9H11ClD5N5 Melting Point N/A
MSDS N/A Flash Point 179.4±23.2 °C

 Use of terbuthylazine d5


Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].

 Names

Name Terbuthylazine D5 (ethyl D5)
Synonym More Synonyms

 terbuthylazine d5 Biological Activity

Description Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Cedergreen N, et al. Does the effect of herbicide pulse exposure on aquatic plants depend on Kow or mode of action? Aquat Toxicol. 2005 Feb 10;71(3):261-271.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 373.1±25.0 °C at 760 mmHg
Molecular Formula C9H11ClD5N5
Molecular Weight 234.741
Flash Point 179.4±23.2 °C
Exact Mass 234.140808
PSA 62.73000
LogP 2.98
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.594

 Synonyms

6-Chloro-N-(H)ethyl-N'-(2-methyl-2-propanyl)-1,3,5-triazine-2,4-diamine
1,3,5-Triazine-2,4-diamine, 6-chloro-N-(1,1-dimethylethyl)-N-(ethyl-d)-
N-tert-Butyl-6-chloro-N'-(H)ethyl-1,3,5-triazine-2,4-diamine