tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate

Modify Date: 2024-01-05 07:14:48

tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure
tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate structure
Common Name tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate
CAS Number 223131-01-9 Molecular Weight 229.316
Density 1.0±0.1 g/cm3 Boiling Point 351.6±11.0 °C at 760 mmHg
Molecular Formula C12H23NO3 Melting Point N/A
MSDS N/A Flash Point 166.4±19.3 °C

 Names

Name tert-butyl cis-(4-hydroxymethyl)cyclohexylcarbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 351.6±11.0 °C at 760 mmHg
Molecular Formula C12H23NO3
Molecular Weight 229.316
Flash Point 166.4±19.3 °C
Exact Mass 229.167801
PSA 58.56000
LogP 1.66
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.485

 Safety Information

HS Code 2924299090

 Synthetic Route

~81%

tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: Almirall, S.A.; Eastwood, Paul Robert; Bach Taña, Jordi; Pages Santacana, Lluis Miquel Patent: EP2554544 A1, 2013 ; Location in patent: Paragraph 0161 ;

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tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: TAISHO PHARMACEUTICAL CO., LTD.; Arena Pharmaceuticals, Inc Patent: WO2005/95357 A2, 2005 ; Location in patent: Page/Page column 109; 110 ; WO 2005/095357 A2

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tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

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tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: Kanuma, Kosuke; Omodera, Katsunori; Nishiguchi, Mariko; Funakoshi, Takeo; Chaki, Shigeyuki; Nagase, Yasuko; Iida, Izumi; Yamaguchi, Jun-ichi; Semple, Graeme; Tran, Thuy-Anh; Sekiguchi, Yoshinori Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 10 p. 3307 - 3319

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tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

~%

tert-Butyl (cis-4-(hydroxymethyl)cyclohexyl)carbamate Structure

tert-Butyl (cis...

CAS#:223131-01-9

Literature: Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-Methyl-2-propanyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate
2-Methyl-2-propanyl [cis-4-(hydroxymethyl)cyclohexyl]carbamate
Carbamic acid, N-[trans-4-(hydroxymethyl)cyclohexyl]-, 1,1-dimethylethyl ester
Carbamic acid, N-[cis-4-(hydroxymethyl)cyclohexyl]-, 1,1-dimethylethyl ester
tert-Butyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate
tert-Butyl [cis-4-(hydroxymethyl)cyclohexyl]carbamate