TRANS-4-(METHYLAMINO)CYCLOHEXANOL

Modify Date: 2024-01-30 12:40:28

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure
TRANS-4-(METHYLAMINO)CYCLOHEXANOL structure
Common Name TRANS-4-(METHYLAMINO)CYCLOHEXANOL
CAS Number 22348-44-3 Molecular Weight 129.200
Density 1.0±0.1 g/cm3 Boiling Point 211.8±33.0 °C at 760 mmHg
Molecular Formula C7H15NO Melting Point N/A
MSDS N/A Flash Point 86.8±16.0 °C

 Names

Name trans-4-(Methylamino)cyclohexanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 211.8±33.0 °C at 760 mmHg
Molecular Formula C7H15NO
Molecular Weight 129.200
Flash Point 86.8±16.0 °C
Exact Mass 129.115356
PSA 32.26000
LogP -0.08
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.480

 Safety Information

Hazard Codes Xi
HS Code 2922199090

 Synthetic Route

~90%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: ALMIRALL, S.A.; AIGUADE BOSCH, Jose; GUAL ROIG, Silvia; PRAT QUINONES, Maria; PUIG DURAN, Carlos Patent: WO2013/68552 A1, 2013 ; Location in patent: Page/Page column 39 ;

~%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: CORTEX PHARMACEUTICALS, INC. Patent: WO2008/143963 A1, 2008 ; Location in patent: Example 51 ;

~80%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: Dehmlow, Henrietta; Ackermann, Jean; Aebi, Johannes; Blum-Kaelin, Denise; Chucholowski, Alexander; Coassolo, Philippe; Hartman, Peter; Kansy, Manfred; Maerki, Hans Peter; Morand, Olivier; Von Der Mark, Elisabeth; Panday, Narendra; Ruf, Armin; Thoma, Ralf; Schulz-Gasch, Tanja Chimia, 2005 , vol. 59, # 3 p. 72 - 76

~%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: Almirall, S.A.; Aiguade Bosch, Jose; Gual Roig, Silvia; Prat Quiñones, María; Puig Duran, Carlos Patent: EP2592077 A1, 2013 ;

~%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: Venuti, Michael C.; Jones, Gordon H.; Alvarez, Robert; Bruno, John J. Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 303 - 318

~%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: Russo,G.; Danieli,B. Gazzetta Chimica Italiana, 1965 , vol. 95, p. 438 - 447

~%

TRANS-4-(METHYLAMINO)CYCLOHEXANOL Structure

TRANS-4-(METHYL...

CAS#:22348-44-3

Literature: CIBA Patent: US2152960 , 1936 ;

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

TRANS-L-4-HYDROXY-PROLINE BENZYL ESTER HCL
L-4-Hydroxy-proline benzyl ester hydrochloride
trans-4-hydroxy-N-methylcyclohexylamine
trans-4-hydroxy-L-proline benzyl ester,hydrochloride
4-(Methylamino)cyclohexanol
Cyclohexanol, 4-(methylamino)-
trans-4-Methylamino-cyclohexanol
trans-4-hydroxymethylcyclohexane carboxylic acid
trans-4-Hydroxy-L-prolin-benzylester,Hydrochlorid
phenylmethyl ester,hydrochloride
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