garenoxacin mesylate

Modify Date: 2024-01-14 16:46:01

garenoxacin mesylate structure	Common Name	garenoxacin mesylate
	CAS Number	223652-82-2	Molecular Weight	522.52
	Density	1.421g/cm3	Boiling Point	581.5ºC at 760mmHg
	Molecular Formula	C₂₄H₂₄F₂N₂O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	305.5ºC

Use of garenoxacin mesylate

Garenoxacin (BMS 284756) mesylate is an orally active quinolone antibiotic and Garenoxacin mesylate has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes. Garenoxacin mesylate also inhibits Gyrase and TOPO IV[1][2][3][4].

Name	garenoxacin mesylate
Synonym	More Synonyms

Description	Garenoxacin (BMS 284756) mesylate is an orally active quinolone antibiotic and Garenoxacin mesylate has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes. Garenoxacin mesylate also inhibits Gyrase and TOPO IV[1][2][3][4].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	1.25 μg/mL (Gyrase), 1.5-2.5 μg/mL (TOPO IV)[2]
References	[1]. Waites KB, et al. In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother. 2003 Jan;47(1):161-5. [2]. Ince D, et al. Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone. Antimicrob Agents Chemother. 2002 Nov;46(11):3370-80. [3]. Zhao X, et al. Mutant prevention concentration of garenoxacin (BMS-284756) for ciprofloxacin-susceptible or -resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2003 Mar;47(3):1023-7. [4]. Azoulay-Dupuis E, et al. Activities of garenoxacin against quinolone-resistant Streptococcus pneumoniae strains in vitro and in a mouse pneumonia model. Antimicrob Agents Chemother. 2004 Mar;48(3):765-73.

Density	1.421g/cm3
Boiling Point	581.5ºC at 760mmHg
Molecular Formula	C₂₄H₂₄F₂N₂O₇S
Molecular Weight	522.52
Flash Point	305.5ºC
Exact Mass	522.12700
PSA	143.31000
LogP	5.38080

Garenoxacin Mesilate

garenoxacin mesylate

Use of garenoxacin mesylate

Names

garenoxacin mesylate Biological Activity

Chemical & Physical Properties

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