JWD-065

Modify Date: 2024-08-15 13:34:19

JWD-065 Structure
JWD-065 structure
Common Name JWD-065
CAS Number 2250287-34-2 Molecular Weight 462.572
Density N/A Boiling Point N/A
Molecular Formula C24H26N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JWD-065


JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.

 Names

Name JWD-065

 JWD-065 Biological Activity

Description JWD-065 is a potent small molecule HIPK2 kinase inhibitor, blocks HIPK2 phosphorylation on S359/T360 and JNK activation in HEK293 cells and attenuates ER stress-induced cell death with EC50 of 641 nM.
References 1. Sebum Lee, et al. Neuron. 2016, 91(1), 41-55. 2. Miduturu CV et al. Chem Biol. 2011;18:868–879.

 Chemical & Physical Properties

Molecular Formula C24H26N6O2S
Molecular Weight 462.572