Cilofexor tromethamine

Cilofexor tromethamine Structure
Cilofexor tromethamine structure
Common Name Cilofexor tromethamine
CAS Number 2253764-93-9 Molecular Weight 707.99
Density N/A Boiling Point N/A
Molecular Formula C32H33Cl3N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cilofexor tromethamine


Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.

 Names

Name Cilofexor tromethamine

 Cilofexor tromethamine Biological Activity

Description Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.

 Chemical & Physical Properties

Molecular Formula C32H33Cl3N4O8
Molecular Weight 707.99
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