ALK2-IN-2

Modify Date: 2024-04-05 14:45:48

ALK2-IN-2 Structure
ALK2-IN-2 structure
Common Name ALK2-IN-2
CAS Number 2254409-25-9 Molecular Weight 497.61
Density N/A Boiling Point N/A
Molecular Formula C28H27N5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK2-IN-2


ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].

 Names

Name ALK2-IN-2

 ALK2-IN-2 Biological Activity

Description ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].
Related Catalog
Target

ALK2:9 nM (IC50)

References

[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.

 Chemical & Physical Properties

Molecular Formula C28H27N5O2S
Molecular Weight 497.61

 Safety Information

Hazard Codes Xi