Symphytine

Modify Date: 2024-01-09 17:52:03

Symphytine Structure
Symphytine structure
Common Name Symphytine
CAS Number 22571-95-5 Molecular Weight 381.46300
Density N/A Boiling Point N/A
Molecular Formula C20H31NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Symphytine


Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1].

 Names

Name symphytine
Synonym More Synonyms

 Symphytine Biological Activity

Description Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1].
Related Catalog
In Vivo Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma[1]. Animal Model: Male inbred ACI rats[1] Dosage: 13 mg/kg Administration: Intraperitoneal injection; 330 days Result: Led to hepatic tumor in rats.
References

[1]. Hirono,et al.Induction of Hepatic Tumors in Rats by Senkirkine and Symphytine. J Natl Cancer Inst. 1979 Aug;63(2):469-72.

 Chemical & Physical Properties

Molecular Formula C20H31NO6
Molecular Weight 381.46300
Exact Mass 381.21500
PSA 96.30000
LogP 1.12770

 Safety Information

RIDADR UN 1544

 Synonyms

myoporoside
(1R,7aR)-7-{[(2,3-Dihydroxy-2-isopropylbutanoyl)oxy]methyl}-2,3,5 ,7a-tetrahydro-1H-pyrrolizin-1-yl (2E)-2-methyl-2-butenoate
myoscorpine
Ajugol