DBCO-PEG4-VC-PAB-DMEA-PNU-159682

Modify Date: 2024-07-22 17:02:03

DBCO-PEG4-VC-PAB-DMEA-PNU-159682 Structure
DBCO-PEG4-VC-PAB-DMEA-PNU-159682 structure
Common Name DBCO-PEG4-VC-PAB-DMEA-PNU-159682
CAS Number 2259318-56-2 Molecular Weight 1695.81
Density N/A Boiling Point N/A
Molecular Formula C86H106N10O26 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG4-VC-PAB-DMEA-PNU-159682


DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].

 Names

Name DBCO-PEG4-VC-PAB-DMEA-PNU-159682

 DBCO-PEG4-VC-PAB-DMEA-PNU-159682 Biological Activity

Description DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].
Related Catalog
Target

Duocarmycins

References

[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

 Chemical & Physical Properties

Molecular Formula C86H106N10O26
Molecular Weight 1695.81
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