LB42908

Modify Date: 2024-02-26 17:54:02

LB42908 Structure
LB42908 structure
Common Name LB42908
CAS Number 226927-89-5 Molecular Weight 533.62000
Density N/A Boiling Point N/A
Molecular Formula C32H31N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LB42908


LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras..

 Names

Name [1-{[1-(1,3-benzodioxole-5-ylmethyl)-1H-imidazole-5-yl]methyl}-4-(1-naphthyl)-1H-pyrrole-3yl](4-methyl-1-piperazinyl)methanone
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C32H31N5O3
Molecular Weight 533.62000
Exact Mass 533.24300
PSA 64.76000
LogP 4.59350

 Synonyms

LB-42908
1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4-methylpiperazin-1-yl)carbonyl-4-(naphthalen-1-yl)-1H-pyrrole
1-[1-(3,4-methylenedioxybenzyl)-1H-imidazol-5-ylmethyl]-3-(4methylpiperazin-1-yl)carbonyl-4(naphthalen-1-yl)-1H-pyrrole