2-Methylphenylalanine hydrochloride (1:1)

Modify Date: 2024-01-02 16:13:15

2-Methylphenylalanine hydrochloride (1:1) Structure
2-Methylphenylalanine hydrochloride (1:1) structure
Common Name 2-Methylphenylalanine hydrochloride (1:1)
CAS Number 22888-51-3 Molecular Weight 179.216
Density 1.2±0.1 g/cm3 Boiling Point 326.2±30.0 °C at 760 mmHg
Molecular Formula C10H13NO2 Melting Point 218.4-220.6 °C
MSDS N/A Flash Point 151.1±24.6 °C

 Names

Name dl-2'-methylphenylalanine hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 326.2±30.0 °C at 760 mmHg
Melting Point 218.4-220.6 °C
Molecular Formula C10H13NO2
Molecular Weight 179.216
Flash Point 151.1±24.6 °C
Exact Mass 179.094635
PSA 63.32000
LogP 1.57
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.568
Storage condition 0-6°C

 MSDS

Name: DL-2 -Methylphenylalanine Hydrochloride Material Safety Data Sheet
Synonym: None Known
CAS: 22888-51-3
Section 1 - Chemical Product MSDS Name:DL-2 -Methylphenylalanine Hydrochloride Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
22888-51-3 DL-2'-Methylphenylalanine Hydrochlorid 98 unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Keep refrigerated. (Store below 4C/39F.)

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 22888-51-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 218.4-220.6 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H13NO2HCl
Molecular Weight: 215.5565

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 22888-51-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
DL-2'-Methylphenylalanine Hydrochloride - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 22888-51-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 22888-51-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 22888-51-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Safety Phrases S24/25
HS Code 2922499990

 Synthetic Route

~76%

2-Methylphenylalanine hydrochloride (1:1) Structure

2-Methylphenyla...

CAS#:22888-51-3

Literature: Pirrung, Michael C.; Krishnamurthy, N. Journal of Organic Chemistry, 1993 , vol. 58, # 4 p. 957 - 958

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2-Methylphenylalanine hydrochloride (1:1) Structure

2-Methylphenyla...

CAS#:22888-51-3

Literature: Journal of Organic Chemistry, , vol. 58, # 4 p. 957 - 958

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2-Methylphenylalanine hydrochloride (1:1) Structure

2-Methylphenyla...

CAS#:22888-51-3

Literature: Journal of the American Chemical Society, , vol. 79, p. 4229,4230

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2-Methylphenylalanine hydrochloride (1:1) Structure

2-Methylphenyla...

CAS#:22888-51-3

Literature: Journal of Medicinal Chemistry, , vol. 34, # 10 p. 3125 - 3132

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

(+-)-2-Amino-3-o-tolyl-propionsaeure
DL-2-Me-Phe-OH
2-Methyl-phenylalanin
DL-o-Methylphenylalanin
2-Methylphenylalanine
2-Methy-DL-Phenylalanine
D,L-o-methylphenylalanine
DL-2'-METHYLPHE HCL
DL-2'-METHYLPHENYLAL
DL-2-METHYLPHENYLALANINE
2-amino-3-(2-methylphenyl)propanoic acid
Phenylalanine, 2-methyl-
Phenylalanine, 2-methyl-, hydrochloride (1:1)
O-METHYL-DL-PHENYLALANINE
2-METHYL-DL-PHENYLALANINE
2-Methylphenylalanine hydrochloride (1:1)
MFCD01320672
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