Licarin A

Modify Date: 2024-01-07 16:35:16

Licarin A structure	Common Name	Licarin A
	CAS Number	23518-30-1	Molecular Weight	326.386
	Density	1.2±0.1 g/cm3	Boiling Point	452.0±45.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	227.2±28.7 °C

Use of Licarin A

(±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. (±)-Licarin A displays 58.7% parasite lysis and has an IC50 value of 100.8 µM for trypanocidal activity against trypomastigote forms of T. cruzi. And (±)-Licarin A shows 100% parasites mortality at 200 µM[1].

Name	2-Methoxy-4-{(2S,3S)-7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2, 3-dihydro-1-benzofuran-2-yl}phenol
Synonym	More Synonyms

Description	(±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. (±)-Licarin A displays 58.7% parasite lysis and has an IC50 value of 100.8 µM for trypanocidal activity against trypomastigote forms of T. cruzi. And (±)-Licarin A shows 100% parasites mortality at 200 µM[1].
Related Catalog	Research Areas >> Infection
References	[1]. Meleti VR, et al. (±)-licarin A and its semi-synthetic derivatives: in vitro and in silico evaluation of trypanocidaland schistosomicidal activities. Acta Trop. 2019 Oct 29:105248.

Density	1.2±0.1 g/cm3
Boiling Point	452.0±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₄
Molecular Weight	326.386
Flash Point	227.2±28.7 °C
Exact Mass	326.151794
PSA	47.92000
LogP	4.19
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.596