8-bromo-Cyclic AMP
8-bromo-Cyclic AMP structure
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Common Name | 8-bromo-Cyclic AMP | ||
|---|---|---|---|---|
| CAS Number | 23583-48-4 | Molecular Weight | 408.10200 | |
| Density | 2.8 g/cm3 | Boiling Point | 741.9ºC at 760 mmHg | |
| Molecular Formula | C10H11BrN5O6P | Melting Point | 254ºC (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 402.5ºC | |
Use of 8-bromo-Cyclic AMP8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase. |
| Name | 8-bromo-3',5'-cyclic AMP |
|---|---|
| Synonym | More Synonyms |
| Density | 2.8 g/cm3 |
|---|---|
| Boiling Point | 741.9ºC at 760 mmHg |
| Melting Point | 254ºC (dec.)(lit.) |
| Molecular Formula | C10H11BrN5O6P |
| Molecular Weight | 408.10200 |
| Flash Point | 402.5ºC |
| Exact Mass | 406.96300 |
| PSA | 164.65000 |
| LogP | 0.52630 |
| Appearance of Characters | Powder | Pale Brown |
| Vapour Pressure | 4.12E-23mmHg at 25°C |
| Index of Refraction | 2.037 |
| Storage condition | −20°C |
| Water Solubility | aqueous base: soluble |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29349990 |
|
~73%
8-bromo-Cyclic AMP CAS#:23583-48-4 |
| Literature: LAURAS AS; COCKBAIN, Julian Patent: WO2008/32103 A2, 2008 ; Location in patent: Page/Page column 8-9; 12 ; |
| Precursor 1 | |
|---|---|
| DownStream 1 | |
CAS#:61363-29-9|
Intramitochondrial adenylyl cyclase controls the turnover of nuclear-encoded subunits and activity of mammalian complex I of the respiratory chain.
Biochim. Biophys. Acta 1853(1) , 183-91, (2015) In mammalian cells the nuclear-encoded subunits of complex I are imported into mitochondria, where they are assembled with mt-DNA encoded subunits in the complex, or exchanged with pre-existing copies... |
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Antipruritic mechanisms of topical E6005, a phosphodiesterase 4 inhibitor: inhibition of responses to proteinase-activated receptor 2 stimulation mediated by increase in intracellular cyclic AMP.
J. Dermatol. Sci. 76(3) , 206-13, (2014) Phosphodiesterase 4 (PDE4), which catalyses the conversion of cyclic adenosine 3',5'-monophosphate (cAMP) to 5'-AMP, plays a critical role in the pathogenesis of inflammatory disorders. Pruritus is th... |
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T-2 toxin regulates steroid hormone secretion of rat ovarian granulosa cells through cAMP-PKA pathway.
Toxicol. Lett. 232(3) , 573-9, (2015) T-2 toxin is a secondary metabolite produced by Fusarium genus and is a common contaminant in food and feedstuffs of cereal origin. In porcine granulosa cells(GC), T-2 toxin has been shown to inhibit ... |
| 8-bromo-cAMP |
| Cyclic amp,8-bromo |
| EINECS 245-760-6 |
| 8-BR-CAMP |
| 8-BROMOADENOSINE 3' 5'-CYCLIC |
| B-cAMP |
| MFCD00075580 |
| 8-bromo-adenosine-3',5'-cyclic monophosphate |
| 8-Br-cyclic AMP |
| 8-Bromo-cyclic 3',5'-amp |
| 8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE |
| 8-Bromoadenosine 3',5'-monophosphate |
| 8-bromo-cyclic AMP |
| 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE |