SRI-37264

Modify Date: 2024-08-09 11:42:00

SRI-37264 Structure
SRI-37264 structure
Common Name SRI-37264
CAS Number 2358714-71-1 Molecular Weight 375.827
Density N/A Boiling Point N/A
Molecular Formula C17H14ClN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SRI-37264


SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation.

 Names

Name SRI-37264

 SRI-37264 Biological Activity

Description SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation.
References 1. Lori A Emert-Sedlak, et al. ACS Infect Dis. 2022 Jan 14;8(1):91-105.

 Chemical & Physical Properties

Molecular Formula C17H14ClN3O3S
Molecular Weight 375.827