BDTX-189
Modify Date: 2024-01-03 10:55:00
BDTX-189 structure
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Common Name | BDTX-189 | ||
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| CAS Number | 2414572-47-5 | Molecular Weight | 561.03 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H29ClN6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BDTX-189BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. |
| Name | BDTX-189 |
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| Description | BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. |
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| Molecular Formula | C29H29ClN6O4 |
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| Molecular Weight | 561.03 |
| Storage condition | -20°C |