(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid

Modify Date: 2024-01-11 16:10:34

(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid structure	Common Name	(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid
	CAS Number	24257-10-1	Molecular Weight	316.478
	Density	0.9±0.1 g/cm3	Boiling Point	428.0±14.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₃₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	324.7±15.2 °C

Use of (all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid

Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.

Name	(6Z,9Z,12Z,15Z,18Z)-henicosa-6,9,12,15,18-pentaenoic acid
Synonym	More Synonyms

Description	Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.
Related Catalog	Research Areas >> Others

Description

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Research Areas >> Others

Density	0.9±0.1 g/cm3
Boiling Point	428.0±14.0 °C at 760 mmHg
Molecular Formula	C₂₁H₃₂O₂
Molecular Weight	316.478
Flash Point	324.7±15.2 °C
Exact Mass	316.240234
PSA	37.30000
LogP	6.80
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.511