NV03
Modify Date: 2024-03-04 18:32:45
NV03 structure
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Common Name | NV03 | ||
|---|---|---|---|---|
| CAS Number | 2448341-58-8 | Molecular Weight | 389.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H27N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NV03NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 is a possible application as anticancer therapeutics [1]. |
| Name | NV03 |
|---|
| Description | NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 is a possible application as anticancer therapeutics [1]. |
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| References | 1. Senisterra G, et al. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. SLAS Discov. 2018 Oct;23(9):930-940. |
| Molecular Formula | C19H27N5O2S |
|---|---|
| Molecular Weight | 389.51 |