demethoxycurcumin

Modify Date: 2024-01-08 15:49:29

demethoxycurcumin Structure
demethoxycurcumin structure
Common Name demethoxycurcumin
CAS Number 24939-17-1 Molecular Weight 338.354
Density 1.3±0.1 g/cm3 Boiling Point 571.4±50.0 °C at 760 mmHg
Molecular Formula C20H18O5 Melting Point N/A
MSDS N/A Flash Point 205.5±23.6 °C

 Use of demethoxycurcumin


(E/Z)-Demethoxycurcumin (p-Hydroxycinnamoyl-feruloylmethane) is a curcuminoid isolated from curcuma species, with anticoagulative active[1].

 Names

Name (1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Synonym More Synonyms

 demethoxycurcumin Biological Activity

Description (E/Z)-Demethoxycurcumin (p-Hydroxycinnamoyl-feruloylmethane) is a curcuminoid isolated from curcuma species, with anticoagulative active[1].
Related Catalog
References

[1]. KOSUGE, T.,et al. Studies on active substances in the herbs used for Oketsu (“stagnant blood”) in Chinese medicine. III. On the anticoagulative principles in curcumae rhizoma. CHEMICAL & PHARMACEUTICAL BULLETIN, 1985;33(4):1499–1502.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 571.4±50.0 °C at 760 mmHg
Molecular Formula C20H18O5
Molecular Weight 338.354
Flash Point 205.5±23.6 °C
Exact Mass 338.115417
PSA 83.83000
LogP 3.15
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.660

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Articles27

More Articles
Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids?

Phytother Res. 28(4) , 517-25, (2014)

Alzheimer's disease (AD) is the most common form of dementia. There is limited choice in modern therapeutics, and drugs available have limited success with multiple side effects in addition to high co...

Differential cellular uptake and metabolism of curcuminoids in monocytes/macrophages: regulatory effects on lipid accumulation.

Br. J. Nutr. 112(1) , 8-14, (2014)

We have previously shown that curcumin (CUR) may increase lipid accumulation in cultured human acute monocytic leukaemia cell line THP-1 monocytes/macrophages, but that tetrahydrocurcumin (THC), an in...

Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: an in vitro and in vivo study.

Mol. Nutr. Food. Res. 57(9) , 1586-97, (2013)

Curcumin has been shown to affect platelet-derived growth factor (PDGF)- and tumor necrosis factor (TNF)-α-elicited vascular smooth muscle cell (VSMC) migration and inhibit neointima formation followi...

 Synonyms

(1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
monodemethoxycurcumin
Feruloyl-P-hydroxycinnnamoylmethane
curcumin II
(1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-
BHCFM
demethoxy curcumin
1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)-
demethoxycurcumin
desmethoxycurcumin
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