Adenosine, 4'-thio-

Modify Date: 2024-01-12 21:28:57

Adenosine, 4'-thio- Structure
Adenosine, 4'-thio- structure
Common Name Adenosine, 4'-thio-
CAS Number 2500-80-3 Molecular Weight 283.31
Density 2.08g/cm3 Boiling Point 657.8ºC at 760mmHg
Molecular Formula C10H13N5O3S Melting Point N/A
MSDS N/A Flash Point 351.6ºC

 Use of Adenosine, 4'-thio-


4’-Thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name Adenosine, 4'-thio
Synonym More Synonyms

 Adenosine, 4'-thio- Biological Activity

Description 4’-Thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.08g/cm3
Boiling Point 657.8ºC at 760mmHg
Molecular Formula C10H13N5O3S
Molecular Weight 283.31
Flash Point 351.6ºC
Exact Mass 283.07400
PSA 155.61000

 Synonyms

4'-thio-adenosine