H-Phe-Phe-OH

Modify Date: 2024-01-02 16:23:25

H-Phe-Phe-OH Structure
H-Phe-Phe-OH structure
 Common Name H-Phe-Phe-OH
CAS Number 2577-40-4 Molecular Weight 312.363
Density 1.2±0.1 g/cm3 Boiling Point 582.8±50.0 °C at 760 mmHg
Molecular Formula C18H20N2O3 Melting Point N/A
MSDS USA Flash Point 306.2±30.1 °C

 Use of H-Phe-Phe-OH


H-Phe-Phe-OH is a peptide made of two phenylalanine molecules; Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine.

 Names

Name Phe-Phe
Synonym More Synonyms

 H-Phe-Phe-OH Biological Activity

Description H-Phe-Phe-OH is a peptide made of two phenylalanine molecules; Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro H-Phe-Phe-OH (Phe-Phe) is a peptide made of two phenylalanine molecules. Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine. It is the precursor of catecholamines in the body. The psychotropic drugs (mescaline, morphine, codeine, and papaverine) also have phenylalanine as a constituent. The H-Phe-Phe-OH recognition motif of the Alzheimer's Abeta peptide is the smallest peptide able to assemble into higher -order structures[1].
References

[1]. de Groot NS, et al. Ile-phe dipeptide self-assembly: clues to amyloid formation. Biophys J. 2007 Mar 1;92(5):1732-41

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 582.8±50.0 °C at 760 mmHg
Molecular Formula C18H20N2O3
Molecular Weight 312.363
Flash Point 306.2±30.1 °C
Exact Mass 312.147400
PSA 92.42000
LogP 2.48
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.605
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2924299090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles25

More Articles
Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry.

Electrophoresis 35(23) , 3321-30, (2014)

There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafil...

Possible mechanism of uptake for several compounds in ionized form through human erythrocyte membrane.

Life Sci. 34(5) , 427-36, (1984)

The mechanism underlying uptake of certain compounds in ionized form across human red blood cell membrane was examined. The ionized forms of salicylate, 5-methoxy-salicylate and phenylalanylphenylalan...

pH-dependence of complexion constants and complex mobility in capillary electrophoresis separations of dipeptide enantiomers.

Electrophoresis 22(15) , 3163-70, (2001)

The chiral separation of the LL- and DD-enantiomers of the dipeptides Ala-Tyr, Phe-Phe, and Asp-PheOMe has been investigated at pH 2.5 and pH 3.5 using beta-cyclodextrin (beta-CD), heptakis-(2,6-di-O-...

 Synonyms

L-Phe-L-Phe-OH
Phe-Phe
l-Phe-l-Phe
L-Phenylalanyl-L-phenylalanine
(S)-2-((S)-2-Amino-3-phenylpropanamido)-3-phenylpropanoic acid
L-Phenylalanyl-L-phenylalanine Di-L-phenylalanine
Di-L-phenylalanine
Phenylalanyl-phenylalanine
L-Phenylalanine, L-phenylalanyl-
2-[(2-amino-3-phenylpropanoyl)amino]-3-phenylpropanoic acid
H-Phe-Phe-OH
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