CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UU9351600
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CHEMICAL NAME :
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9H-Pyrido(2,3-b)indole, 2-amino-
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CAS REGISTRY NUMBER :
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26148-68-5
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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18
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MOLECULAR FORMULA :
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C11-H9-N3
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MOLECULAR WEIGHT :
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183.23
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WISWESSER LINE NOTATION :
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T B656 FN HMJ EZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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37600 mg/kg/98W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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50424 mg/kg/82W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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44712 mg/kg/89W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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41400 mg/kg/98W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
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TYPE OF TEST :
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Specific locus test
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TYPE OF TEST :
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Mutation in mammalian somatic cells
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Rodent - hamster Lung
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DOSE/DURATION :
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50 mg/L
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,91,1983 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,245,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,245,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
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![2-Nitro-9H-pyrido[2,3-b]indole structure](https://image.chemsrc.com/caspic/303/176853-91-1.png)
CAS#:176853-91-1