5-Chloro-2-methyl-4-isothiazolin-3-one

Modify Date: 2024-01-02 16:32:54

5-Chloro-2-methyl-4-isothiazolin-3-one structure	Common Name	5-Chloro-2-methyl-4-isothiazolin-3-one
	CAS Number	26172-55-4	Molecular Weight	149.599
	Density	1.5±0.1 g/cm3	Boiling Point	200.2±50.0 °C at 760 mmHg
	Molecular Formula	C₄H₄ClNOS	Melting Point	42-45?C
	MSDS	N/A	Flash Point	74.9±30.1 °C

Name	chloromethylisothiazolinone
Synonym	More Synonyms

Density	1.5±0.1 g/cm3
Boiling Point	200.2±50.0 °C at 760 mmHg
Melting Point	42-45?C
Molecular Formula	C₄H₄ClNOS
Molecular Weight	149.599
Flash Point	74.9±30.1 °C
Exact Mass	148.970215
PSA	50.24000
LogP	0.24
Vapour Pressure	0.3±0.4 mmHg at 25°C
Index of Refraction	1.628
Stability	Stable. Incompatible with strong oxidizing agents.

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: 5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, ¿14% in water. CMI/MI ¿2.0
Synonyms:CMI

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, ¿14% in water. CMI/MI ¿2.0
CAS number:26172-55-4

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C4H4ClNOS
Molecular weight:149.6

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX8156850

CHEMICAL NAME :: 4-Isothiazolin-3-one, 5-chloro-2-methyl-

CAS REGISTRY NUMBER :: 26172-55-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C4-H4-Cl-N-O-S

MOLECULAR WEIGHT :: 149.60

WISWESSER LINE NOTATION :: T5SNVJ B1 EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 200 ng/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,129,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3204 No. of Facilities: 2332 (estimated) No. of Industries: 24 No. of Occupations: 25 No. of Employees: 42106 (estimated) No. of Female Employees: 17003 (estimated)

Hazard Codes	C:Corrosive
Risk Phrases	R20/21/22;R34;R43;R50
Safety Phrases	S26-S36/37/39-S45-S60-S61-S24-S28
RIDADR	UN 1760 8/PG 2
WGK Germany	1
RTECS	NX8156850
Packaging Group	III
Hazard Class	8
HS Code	2934999090