RMS-07

Modify Date: 2024-01-09 21:42:18

RMS-07 Structure
RMS-07 structure
Common Name RMS-07
CAS Number 2645409-78-3 Molecular Weight 604.74
Density N/A Boiling Point N/A
Molecular Formula C35H40N8O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RMS-07


RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region[1].

 Names

Name RMS-07

 RMS-07 Biological Activity

Description RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region[1].
Related Catalog
Target

IC50:13.1 nM (Monopolar Spindle Kinase 1 (MPS1/TTK)).

References

[1]. Ricardo A M Serafim, et al. Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. J Med Chem. 2022 Feb 24;65(4):3173-3192.

 Chemical & Physical Properties

Molecular Formula C35H40N8O2
Molecular Weight 604.74
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