P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester

Modify Date: 2024-04-05 20:50:14

P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester Structure
P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester structure
Common Name P-(1-Aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidic acid ethyl ester
CAS Number 26594-10-5 Molecular Weight 301.23900
Density 1.469g/cm3 Boiling Point 504ºC at 760 mmHg
Molecular Formula C10H16N5O4P Melting Point N/A
MSDS N/A Flash Point 258.6ºC

 Names

Name N-[amino(ethoxy)phosphoryl]-N-[4-(aziridin-1-yl)-5-methoxypyrimidin-2-yl]formamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.469g/cm3
Boiling Point 504ºC at 760 mmHg
Molecular Formula C10H16N5O4P
Molecular Weight 301.23900
Flash Point 258.6ºC
Exact Mass 301.09400
PSA 120.46000
LogP 1.77250
Vapour Pressure 2.76E-10mmHg at 25°C
Index of Refraction 1.613

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SZ6180000
CHEMICAL NAME :
Phosphonamidic acid, P-1-aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl) -, ethyl ester
CAS REGISTRY NUMBER :
26594-10-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H16-N5-O4-P
MOLECULAR WEIGHT :
301.28
WISWESSER LINE NOTATION :
T6N CNJ EO1 BMVMPO&O2&- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 4,308,1970

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

P-1-Aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl)phosphonamidic acid ethyl ester
Phosphonamidic acid,P-1-aziridinyl-N-((5-methoxy-2-pyrimidinyl)carbamoyl)-,ethyl ester
N-Monoethyleneamidomonoethoxyphosphono-N'-5-methoxypyrimidyl-2-urea
ethyl n-[4-(aziridin-1-yl)-5-methoxypyrimidin-2-yl]-n-formylphosphorodiamidate
P-aziridin-1-yl-N-(5-methoxy-pyrimidin-2-ylcarbamoyl)-phosphonamidic acid ethyl ester