N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine

Modify Date: 2024-07-18 13:49:24

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine structure
Common Name N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine
CAS Number 267243-68-5 Molecular Weight 431.89100
Density N/A Boiling Point N/A
Molecular Formula C21H23ClFN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-N-(3-chloro-4-fluorophenyl)-7-(3-morpholin-4-ylpropoxy)quinazoline-4,6-diamine
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C21H23ClFN5O2
Molecular Weight 431.89100
Exact Mass 431.15200
PSA 85.53000
LogP 4.44130

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~98%

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Warner-Lambert Company Patent: US6344455 B1, 2002 ; US 6344455 B1

~78%

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Warner-Lambert Company LLC Patent: US6664390 B2, 2003 ; Location in patent: Page column 8-9 ;

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Detail
Literature: Barth, Hubert; Steiner, Klaus; Schneider, Simon Patent: US2003/50313 A1, 2003 ;

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N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

~%

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

~%

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

~%

N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine Structure

N4-(3-Chloro-4-...

CAS#:267243-68-5

Literature: Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6-amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholino)propoxy]quinazoline
(3-chloro-4-fluorophenyl)-[7-(3-morpholino-4-yl-propoxy)-6-aminoquinazolin-4-yl]-amine
6-amino-4-[N-(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]quinazoline
N*4*-(3-chloro-4-fluoro-phenyl)-7-(3-morpholin-4-yl-propoxy)-quinazoline-4,6-diamine
(3-CHLORO-4-FLUOROPHENYL)-[7-(3-MORPHOLIN-4-YL-PROPOXY)-6-AMINO-QUINAZOLINE-4-YL]-AMINE
N4-(3-chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazolin-4,6-diamine
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine
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