RET-IN-14 structure
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Common Name | RET-IN-14 | ||
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CAS Number | 2755843-62-8 | Molecular Weight | 506.49 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C24H23FN8O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of RET-IN-14RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research[1] |
Name | RET-IN-14 |
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Description | RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research[1] |
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Related Catalog | |
References |
[1]. Jing Wang, et al. Compounds with macrocyclic structure and their uses. WO2021244609A1. |
Molecular Formula | C24H23FN8O4 |
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Molecular Weight | 506.49 |