MRL-1237

Modify Date: 2024-02-10 01:13:05

MRL-1237 Structure
MRL-1237 structure
Common Name MRL-1237
CAS Number 276704-21-3 Molecular Weight 354.813
Density N/A Boiling Point N/A
Molecular Formula C19H16ClFN4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRL-1237


MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant.

 Names

Name MRL-1237

 MRL-1237 Biological Activity

Description MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant.
References References 1. Shimizu H, et al. J Virol. 2000 May;74(9):4146-54. 2. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30. View Related Products by Target Enterovirus

 Chemical & Physical Properties

Molecular Formula C19H16ClFN4
Molecular Weight 354.813
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