4-diethoxy-phosphoryl-methylbenzoic acid

Modify Date: 2024-01-08 22:38:36

4-diethoxy-phosphoryl-methylbenzoic acid structure	Common Name	4-diethoxy-phosphoryl-methylbenzoic acid
	CAS Number	28149-48-6	Molecular Weight	272.234
	Density	1.2±0.1 g/cm3	Boiling Point	427.9±38.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₇O₅P	Melting Point	N/A
	MSDS	N/A	Flash Point	212.6±26.8 °C

Name	4-(diethoxyphosphorylmethyl)benzoic acid
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	427.9±38.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₇O₅P
Molecular Weight	272.234
Flash Point	212.6±26.8 °C
Exact Mass	272.081360
PSA	82.64000
LogP	1.74
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.518

4-Bromomethylbe...

CAS#:6232-88-8

Triethyl phosphite

CAS#:122-52-1

~96%

4-diethoxy-phos...

CAS#:28149-48-6

Literature: AXYS PHARMACEUTICALS, INC. Patent: WO2005/118584 A2, 2005 ; Location in patent: Page/Page column 68-69 ;

Methyl 4-(bromo...

CAS#:2417-72-3

Triethyl phosphite

CAS#:122-52-1

~84%

4-diethoxy-phos...

CAS#:28149-48-6

Literature: Bardecker, Julie A.; Afzali, Ali; Tulevski, George S.; Graham, Teresita; Hannon, James B.; Jen, Alex K.-Y. Journal of the American Chemical Society, 2008 , vol. 130, # 23 p. 7226 - 7227

4-Bromomethylbe...

CAS#:6232-88-8

4-diethoxy-phos...

CAS#:28149-48-6

Literature: G. D. Searle and Co. Patent: US4918064 A1, 1990 ;

4-(Chloromethyl...

CAS#:1642-81-5

Diethyl phosphite

CAS#:762-04-9

~10%

4-diethoxy-phos...

CAS#:28149-48-6

Literature: Laven, Gaston; Kalek, Marcin; Jezowska, Martina; Stawinski, Jacek New Journal of Chemistry, 2010 , vol. 34, # 5 p. 967 - 975

Triethyl phosphate

CAS#:78-40-0

4-Bromomethylbe...

CAS#:6232-88-8

4-diethoxy-phos...

CAS#:28149-48-6

Literature: Chen, Xiaoqi; Kopecky, David J.; Mihalic, Jeff; Jeffries, Shawn; Min, Xiaoshan; Heath, Julie; Deignan, Jeff; Lai, Sujen; Fu, Zice; Guimaraes, Cristiano; Shen, Shanling; Li, Shyun; Johnstone, Sheree; Thibault, Stephen; Xu, Haoda; Cardozo, Mario; Shen, Wang; Walker, Nigel; Kayser, Frank; Wang, Zhulun Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3837 - 3851

Precursor 6
CAS#:6232-88-8 4-Bromomethylbe... CAS#:122-52-1 Triethyl phosphite CAS#:2417-72-3 Methyl 4-(bromo... CAS#:1642-81-5 4-(Chloromethyl...
CAS#:762-04-9 Diethyl phosphite CAS#:78-40-0 Triethyl phosphate
DownStream 4
CAS#:133208-93-2 Ibrolipim CAS#:118578-91-9 4-(diethoxyphos... CAS#:125185-25-3 Diethyl (4-form... CAS#:71441-08-2 ethyl 4-(dietho...

4-[(Diethoxyphosphoryl)methyl]benzoic acid

4-diethoxyphosphinoylmethylbenzoic acid

Benzoic acid, 4-[(diethoxyphosphinyl)methyl]-

diethyl 4-carboxybenzylphosphonic acid

F9995-0119

4-diethoxy-phosphoryl-methylbenzoic acid

4-diethoxy-phosphoryl-methylbenzoic acid

Names

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms